DNRF’s 12th Chair Grant funds research in gene regulatory mechanisms
Professor Vijay Tiwari, at the Department of Molecular Medicine, has received a DNRF Chair grant of 10 million DKK to work on revealing gene regulatory mechanisms crucial to the development of cerebral cortex and its disruption in neurodevelopmental disorders.
Cortical expansion and folding are crucial to brain evolution and function, while defects in these processes associate with neurodevelopmental disorders such as epilepsy and intellectual disability.
– Mammalian brain development involves highly complex and organized sets of events. We aim to reveal gene regulatory mechanisms governing spatiotemporal specification of cell-fates underlying these processes and reveal novel developmental and genetic risk factors for associated disorders, Vijay Tiwari explained.
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