Copenhagen Center for Glycomics (CCG)

Information

Center leader:

Professor Henrik Clausen

Period:

2012 - 2021

Application round:

7th Round

Host institution(s)

University of Copenhagen

Grant:

103.3M DKK

Copenhagen Center for Glycomics (CCG) explores the saccharide chains – complex carbohydrates – that cover the surface of our proteins and cells. Complex carbohydrates of cells – the glycome – are often regarded as the third language of life after the genome and the proteome.

Defects in the glycome are a major cause of hereditary diseases. The glycome is produced by over 200 enzymes and mutations in their genes lead to defects in the glycome.

The center explores and maps these genes with new enzymatic technologies to turn on and off genes and identify causes of disease. Complex carbohydrates are essential for fundamental cellular processes, and changes in the glycome are involved in e.g. metabolic diseases and cancers.

We develop new methods to detect mutations and the changes these infer the glycome and cellular processes. Insight into the glycome may lead to new diagnostic tools and better-targeted drugs and vaccines.

Annual highlights

Highlights 2019

Highlights 2018

Latest news

CCG discovers a wealth of sugar molecules for developing medications

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CCG develops a new method for mapping important sugars

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Carbohydrate plays a significant role in experiments with rats and the results may lead to new medicines

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