The Center investigates dynamic processes at the molecular level in multicellular organisms and aims to uncover universal principles behind them.
Key questions essential to DynaMo are
- to understand how cellular components, within the crowded cellular milieu, with high coordination and precision are assembled in supramolecular complexes undertaking specific tasks, such as RNA and metabolite-mediated regulation.
- to understand how cellular components are able to ‘read’ the signposts of the organism and find their way to the final destination.
As model system DynaMo uses the plant Arabidopsis thaliana (thale cress) and its defense metabolites, glucosinolates; a unique systems biology model given its extensive bioinformatic and genomic tools.
Ultimately, the Center expects to understand how higher order of structure in biology is obtained which enables a multicellular organism to function, and to sense and respond to the environment.
Watch videos from DynaMo here